履历

2015-至今，山东第一医科大学，免疫学研究所，讲师

2013-2015，西北农林科技大学，兽医免疫生物学，博士后

2009-2012，山东农业大学，预防兽医学，博士研究生

2006-2009，山东农业大学，预防兽医学，硕士研究生

2000-2004，山东农业大学，微生物学，学士

研究领域与方向

   从事免疫调节性T细胞（Regulatory T cells, Treg）相关的研究工作。主要以感染和肿瘤为模型，研究树突状细胞亚群对Treg细胞分化、增殖及功能调控的分子机制，以及能量代谢对Treg细胞发育及功能的影响。

学术荣誉与奖励

泰山医学院第四层次引进人才

关键词

调节性T细胞；树突状细胞；细胞能量代谢；信号通路；免疫耐受

代表性论文

1. Gao, J., S. Xiao, Y. Xiao, X. Wang, C. Zhang, Q. Zhao, Y. Nan, B. Huang, H. Liu, N. Liu, J. Lv, T. Du, Y. Sun, Y. Mu, G. Wang, F.S. Shahid, G. Zhang, J.A. Hiscox, I. Goodfellow, and E.M. Zhou, MYH9 is an Essential Factor for Porcine Reproductive and Respiratory Syndrome Virus Infection. Sci Rep, 2016. 6 (25120).

2. Gao, J., P. Ji, M. Zhang, X. Wang, N. Li, C. Wang, S. Xiao, Y. Mu, Q. Zhao, T. Du, Y. Sun, J.A. Hiscox, G. Zhang, and E.M. Zhou, GP5 expression in Marc-145 cells inhibits porcine reproductive and respiratory syndrome virus infection by inducing beta interferon activity. Vet Microbiol, 2014. 174(3-4): p. 409-18.

3. Gao, J., N. Kong, Y. Xiao, A. Zhang, and E.M. Zhou, Development of real-time PCR methods for the detection of CD163 and porcine reproductive and respiratory syndrome virus N genes in Marc-145 cell. J Ani and Vete Advance, 2012. 11(23): p. 4489-4493.

4. Gao, J., J. Chen, X. Si, Z. Xie, Y. Zhu, X. Zhang, S. Wang, and S. Jiang, Genetic variation of the VP1 gene of the virulent duck hepatitis A virus type 1 (DHAV-1) isolates in Shandong province of China. Virol Sin, 2012. 27(4): p. 248-53.

5. Xiao, Y., Wu, W., Gao, J., Smith, N., Burkard, C., Xia, D., Zhang, M., Wang, C., Archibald, A., Digard, P., Zhou, E. M., Hiscox, J. A., Characterization of the Interactome of the Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 2 Reveals the Hyper Variable Region as a Binding Platform for Association with 14-3-3 Proteins. J Proteome Res, 2016. 15: p1388-1401.

6. Li, N., Yan, Y., Zhang, A., Gao, J., Zhang, C., Wang, X., Hou, G., Zhang, G., Jia, J., Zhou, E. M., Xiao, S. MicroRNA-like viral small RNA from porcine reproductive and respiratory syndrome virus negatively regulates viral replication by targeting the viral nonstructural protein 2. Oncotarget, 2016. 7(50): p. 82902-82920.

7. Li, N., Du, T., Yan, Y., Zhang, A., Gao, J., Hou, G., Xiao, S., Zhou, E. M., MicroRNA let-7f-5p Inhibits Porcine Reproductive and Respiratory Syndrome Virus by Targeting MYH9. Sci Rep, 2016. 6: p. 34332.

8.  Zhang, C., F. Pu, A. Zhang, L. Xu, N. Li, Y. Yan, J. Gao, H. Liu, G. Zhang, I.G. Goodfellow, E.M. Zhou, and S. Xiao, Heme Oxygenase-1 Suppresses Bovine Viral Diarrhoea Virus Replication in vitro. Sci Rep, 2015. 5: p. 15575.

9   Liu, H., Y. Wang, H. Duan, A. Zhang, C. Liang, J. Gao, C. Zhang, B. Huang, Q. Li, N. Li, S. Xiao, and E.M. Zhou, An intracellularly expressed Nsp9-specific nanobody in MARC-145 cells inhibits porcine reproductive and respiratory syndrome virus replication. Vet Microbiol, 2015. 181(3-4): p. 252-60.

10. Xiao, S., A. Zhang, C. Zhang, H. Ni, J. Gao, C. Wang, Q. Zhao, X. Wang, X. Wang, C. Ma, H. Liu, N. Li, Y. Mu, Y. Sun, G. Zhang, J.A. Hiscox, W.H. Hsu, and E.M. Zhou, Heme oxygenase-1 acts as an antiviral factor for porcine reproductive and respiratory syndrome virus infection and over-expression inhibits virus replication in vitro. Antiviral Res, 2014. 110: p. 60-9.

联系方式

Email: jimingao2006@163.com

Phone: +86-0538-8667675